American senior running back Jo’ Kwan Holmes led his team with 93 rushing yards and a touchdown.
Patriots’ defensive back Marquez Jackson grabbed two interceptions and returned them for touchdowns.
He had 110 yards in interception returns.
Up next for American is Oxbridge Academy (6-1) on Friday, October 21, followed by a game that could decide the district title against North Miami Beach on October 27.
Miami Edison ended a long playoff drought by defeating district rival Pace High, 22-15, and the Red Raiders remain undefeated (6-0).
Pace (3-2) trailed 22-7 but scored on an 87-yard drive and covered a two-point conversion.
The Spartans’ defense tried to stop the Red Raiders’ offense to give their team a chance to tie the game.
But Edison’s offense picked up two first downs, including one of 14-yards, that sealed the game.
Up next for Pace is Treasure Coast on Friday, October 21.
Top ranked Booker T. Washington clobbered Hialeah Miami Lakes, 58-10.
The Trojans fall to 1-5 on the season.
HML scored ten points in the second quarter but was shut out for the rest of the game, and allowed the most points against the team this season.
Hialeah Miami Lakes will try to pick up its second win of the season against Gulliver Prep on Friday, October 28.
Doral Academy (6-1) defeated Goleman, 52-26, in a key 7A District game.
Goleman (4-4) will try to bounce back against Ronald Reagan (4-3) on Friday, October 14.
Dr. Krop (3-4) defeated Hialeah Gardens, 35-7.
Hialeah Gardens (1-5) plays North Miami Beach (4-2) on October 21.